CELPHERE™

Microcrystalline Cellulose (MCC) Spherical Seed Core

CELPHERE™ is a 100% microcrystalline cellulose (MCC) spheres.
It is a neutral substrate for manufacturing of microgranules. It has no smell nor odor.

It is insoluble in organic solvents such as ethanol.

Features and functions

CELPHERE™ is used as a neutral substrate for microgranules with the following characteristics:

High sphericity and narrow particle size distribution : Accurate dissolution
Insoluble, optimum water absorption : Low particle agglomeration during the process
High mechanical strength (low friability) : Tolerant with high stress and coating machine varieties
Small particles : High dose layering
Low chemical reactivity : no pre-coating required

Products

CELPHERE™ products range includes five (5) different grades characterized in terms of particle size and density:

Grade	Particle size (µm)	Density (g.cm3)
CELPHERE CP-102	106-212	0.83
CELPHERE CP-203	150-300	0.87
CELPHERE CP-305	300-500	0.97
CELPHERE CP-507	500-710	0.97
CELPHERE CP-708	710-850	0.93

CELPHERE™, from Asahi Kasei Corporation, conforms to the USP/NF; Ph.Eur ; JP(JPE) monograph of MCC.

CELPHERE™ is manufactured following the current excipient Good Manufacturing Practices (GMPs).

The regulatory and quality package is available on request.

Supplier

CELPHERE™ is manufactured by Asahi Kasei Corporation. Asahi Kasei Corporation is a Japanese company who is manufacturing mineral products and cellulose derivatives for a multitude of pharmaceutical applications.

SEPPIC distributes these products in Europe for France, Italy, Portugal, Greece and Belgium.