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Montanide™ range for veterinary vaccines

Adjuvant solutions for animal health
Montanide™ range for veterinary vaccines

To assist researchers in developing veterinary vaccines and improving their efficacy and stability, Seppic has been combining expertise and services for over 40 years, providing a wide range of ready-to-use adjuvants: the Montanide™ range for veterinary vaccines.

The Montanide™ range for veterinary vaccines

Drawing on Seppic's expertise in vaccine adjuvants and immunology, the Montanide™ range is based on three core technologies: emulsions, micro-emulsions, and polymers.

Montanide™ ISA: these oil-based adjuvants are intended for use in water-in-oil (W/O), oil-in-water (O/W) or water-in-oil-in-water (W/O/W) emulsions. Composed of mineral oil, non-mineral oil, or a composition of both — as well as surfactants — these adjuvants are highly robust and ready to emulsify.

Montanide™ IMS: these ready-to-dilute adjuvants contain a mixture of micro-emulsions and an immunostimulant compound. They can be used with several antigens — bacterial, viral, parasitic or subunit — and are available in sterile (ST) or preserved (PR) grades.

Montanide™ GEL: these ready-to-disperse polymeric adjuvants improve the safety profile and efficacy of water-based vaccines. Consisting of a highly stable dispersion of gel particles in water, they can significantly enhance the immune response while maintaining a safety profile equivalent to that of aluminum salts.

Manufacturing quality

Our veterinary adjuvants are manufactured according to International Pharmaceutical Excipient Council (IPEC) manufacturing guidelines at our manufacturing sites in Castres (France) and Qing Pu (China).

Conformity of our ingredients

Montanide™ adjuvants can be used in veterinary applications such as veterinary vaccines based on toxicological tests and our field experience. Of course, each team developing a veterinary vaccine must study the safety and efficacy profiles of their formulations.

Our auxiliaries and their components comply with the regulations in place. They are approved by the CVMP (Committee for Veterinary Medical Products) for use in immunological products. Their components are either included in the list of Authorised Substances in the Annex to European Council Regulation (EU) N° 37/2010 as substances not requiring additional Maximum Residual Limit (MRL) studies, or are considered to be outside the scope of Regulation (EC) N° 470/2009 when used in a veterinary product.