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Animal species and veterinary vaccines

Vaccine adjuvants tailored to each animal species
Seppic Animal species and veterinary vaccines

Animal vaccination guarantees animal protection against diseases. It reduces mortality and dependence on antibiotics, and improves welfare.

For each vaccination program, the choice of vaccine adjuvant is based upon several criteria, including the animal species.

Selecting a veterinary vaccine adjuvant

The adjuvant choice for a veterinary vaccine is based on several criteria in order to stimulate the most appropriate immune responses:

  • The animal species and its sensitivity,
  • The disease,
  • The type of antigen (live or inactivated),
  • The desired kinetics of the immune response (short or long term protection),
  • The type of immune response (humoral and/or cellular),
  • The route of administration (by injection or mucosal).

Our experts can assist each customer in selecting the most suitable Montanide™ adjuvant for their model.

Solutions for avian species

Vaccines are the most commonly administered veterinary drugs in the poultry sector. They contribute to the expansion of poultry farming by helping to prevent and fight against diseases, for instance in animals such as breeding chickens, broilers and laying hens.

Seppic offers adjuvants dedicated to avian vaccines:

  • For injection, the standard recommended technology for inactivated antigens, mono or multivalent, is the water-in-oil (W/O) emulsion with Montanide™ ISA.
  • In mucosal administration, Seppic offers Montanide™ GEL polymeric and Montanide™ IMS micro-emulsions technologies which are compatible with aqueous live or inactivated antigens, effective in stimulating the mucosal immune system, with a high safety profile.
  • For in ovo administration, Seppic provides Montanide™ IMS 1313 VG NST, which meets the needs of fertilized egg vaccination in terms of both safety and efficacy. Vaccinating poultry in hatcheries reduces the cost of vaccinating breeding and laying poultry.

Montanide™ adjuvants are used in avian vaccines against viral, bacterial or parasitic diseases such as E. Coli, Erysipelas, Pasteurella multocida, Reimerella, Salmonella, Coccidiosis, avian influenza, Newcastle Disease (ND), Egg Drop Syndrome (EDS), Infectious Bronchitis (IB) and Marek’s disease

Administration of in ovo vaccines

In ovo vaccination is an effective way of vaccinating breeding and laying poultry in hatcheries. It is routinely used in the poultry sector, particularly for Marek's disease in North America.
This vaccination method consists of injecting vaccines into embryonated eggs after 18 or 19 days of incubation (2-3 days before hatching), using specialized equipment, at a rate of 50,000 to 100,000 eggs per hour.
To develop inactivated or subunit vaccines for in ovo injection, adjuvants must be effective and compatible with fertilized eggs, which is not the case with conventional oil-based vaccines.
Seppic tested placebo vaccines prepared with various adjuvant technologies to determine their safety profiles when injected into eggs 18 days after incubation. For instance, one of our trials in a subunit in ovo Coccidiosis vaccine demonstrated that Montanide™ IMS 1313 VG NST had very high efficacy combined with a good safety profile.

 

Solutions for fish

Vaccinating fish ensures their protection against common viral and bacterial diseases. It significantly reduces mortality, reduces reliance on antibiotics, improves fish welfare, and increases productivity by enhancing growth and feed conversion rates.

Seppic recommends adjuvants suitable for fish vaccines:

Montanide™ adjuvants are used to vaccinate fish against diseases such as Streptococcus, Aeronomas, Vibriosis, Yersinia, Pasteurellosis, and Furunculosis.

Solutions for swine

Vaccination programs contribute to improving animal health in the swine industry. The adjuvant is essential to vaccine efficacy as antigens are increasingly purified. The safety profile of the adjuvant is a key factor in developing vaccines for highly susceptible animals such as swine.

Seppic recommends adjuvants that meet expectations in terms of swine vaccine development:

Montanide™ adjuvants are used in vaccines for pigs, sows and piglets against viral, bacterial or parasitic diseases such as Foot and Mouth Disease (FMD), Aujeszky's disease, porcine parvovirus, Porcine Reproductive and Respiratory Syndrome (PRRS), Actinobacillus pleuropneumoniae (APP), Pasteurella multocida, Mycoplasma Hyopneumoniae, Bordetella bronchiseptica, and Streptococcus suis.

Solutions for cattle and small ruminants

Since the 1930s, vaccines, by protecting against diseases, have significantly improved the health and well-being of cattle and small ruminants. Vaccine adjuvants play a key role in stimulating their immune systems. The selection of a proper adjuvant is therefore essential to achieve effective protection while maintaining a high safety profile.

Montanide™ adjuvants are used in vaccines intended for both cattle and small ruminants against viral, bacterial or parasitic diseases such as Foot and Mouth Disease (FMD), rotavirus, coronavirus, Clostridium Botilunum, haemorrhagic septicaemia, and E. Coli.

MONTANIDE™ offer for cattle and small ruminants vaccines

Solutions for pets and horses

Pets and horses can suffer from a wide range of infectious diseases. For their health and well-being, disease prevention with well-tolerated vaccines is a top priority. Seppic recommends Montanide™ IMS micro-emulsions and Montanide™ GEL polymer technology for effective vaccines with a high safety profile for these sensitive animals.

Montanide™ adjuvants have been successfully tested in field trials and projects for the vaccination of horses, cats, and dogs against various pathogens, such as rabies, influenza, canine parvovirosis, leptospira, and rhodococcus equi.

High safety profile for sensitive animals