SEPPIC launches SUBLIGANA™, an active ingredient for anti-imperfection, anti-spot & flawless-looking complexion concepts related to oxidative stress, designed by Serdex a subsidiary of SEPPIC since January 2017.
Acne is affecting about 80% of persons at some point in their lives(1). New studies have shown that an increased cutaneous and systemic oxidative stress is involved (2).
SUBLIGANA™ is a titrated extract of Harungana madagascariensis originated from the center and east of Madagascar. By forming a physical and a repulsive barrier, Harungana madagascariensis protects primary forest areas from attacks and is capable of restoring degraded landscapes. It is considered by botanists as a “forest Guard”. Traditionally, leaf decoctions are used against asthma and skin disorders and leaf juice is used for wound healing.
SUBLIGANA™ addresses blemished skin and acne-prone skin. An in-use test on teenagers presenting acne-prone skin showed a significant whiteheads reduction versus placebo after 28 days. SUBLIGANA™ mechanism of action combines soothing effect (lipase inhibition, IL-10 and IL-12 regulation), antioxidant effect (protection against lipid peroxidation) and efficacy against Propionibacterium acnes.
Harungana madagascariensis leaves are collected under good collecting practices in the high plateaus area in Madagascar to ensure a repeatable and reliable phytochemical composition. Overall, Serdex is committed to the principles of the Nagoya Protocol and implements practices for fair and equitable sharing of benefits.
SUBLIGANA™ is China compliant (IECIC listed) and Cosmos compliant.
Virginie Anchartéchahar, R&D Manager for Serdex confirms: “On the basis of scientific results, we have developed an original mechanism of action focusing on soothing and anti-oxidant effect to address acne-prone skin.”
References
1: Questions and Answers About Acne. National Institute of Arthritis and Musculoskeletal and Skin Diseases, 2001, jan 2006 [consulted in july 2016]. Available on: www.niams.nih.gov/Health_Info/Acne
2: Bowe et al.. Clinical implications of lipid peroxidation in acne vulgaris old wine in new bottles, Lipids in Health and Disease 2010.
