SEPPIC discloses SUBLIGANA™, an anti-imperfection active ingredient for blemished and acne-prone skin

  • April 3, 2017
  • 2 mins of read time

SEPPIC discloses SUBLIGANA™, an anti-imperfection active ingredient for blemished and acne-prone skin

SEPPIC launches SUBLIGANA™, an active ingredient for anti-imperfection, anti-spot & flawless-looking complexion concepts related to oxidative stress, designed by Serdex a subsidiary of SEPPIC since January 2017.

Acne is affecting about 80% of persons at some point in their lives(1). New studies have shown that an increased cutaneous and systemic oxidative stress is involved (2).

SUBLIGANA™ is a titrated extract of Harungana madagascariensis originated from the center and east of Madagascar. By forming a physical and a repulsive barrier, Harungana madagascariensis protects primary forest areas from attacks and is capable of restoring degraded landscapes. It is considered by botanists as a “forest Guard”. Traditionally, leaf decoctions are used against asthma and skin disorders and leaf juice is used for wound healing.

SUBLIGANA™ addresses blemished skin and acne-prone skin. An in-use test on teenagers presenting acne-prone skin showed a significant whiteheads reduction versus placebo after 28 days. SUBLIGANA™ mechanism of action combines soothing effect (lipase inhibition, IL-10 and IL-12 regulation), antioxidant effect (protection against lipid peroxidation) and efficacy against Propionibacterium acnes.

Harungana madagascariensis leaves are collected under good collecting practices in the high plateaus area in Madagascar to ensure a repeatable and reliable phytochemical composition. Overall, ​Serdex is committed to the principles of the Nagoya Protocol and implements practices for fair and equitable sharing of benefits.

SUBLIGANA™ is China compliant (IECIC listed) and Cosmos compliant.

Virginie Anchartéchahar, R&D Manager for Serdex confirms: “On the basis of scientific results, we have developed an original mechanism of action focusing on soothing and anti-oxidant effect to address acne-prone skin.

1: Questions and Answers About Acne. National Institute of Arthritis and Musculoskeletal and Skin Diseases, 2001, jan 2006 [consulted in july 2016]. Available on:
2: Bowe et al.. Clinical implications of lipid peroxidation in acne vulgaris old wine in new bottles, Lipids in Health and Disease 2010.

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Alexandra Gilbert
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