Adjuvant selection will consider the type of oil and the ratio of use (from 50% to 70%) depending on expected vaccine characteristics.
MONTANIDE™ ISA for W/O emulsions - Application
These very efficient adjuvants are used to achieve a long-term protective immune response.
Field trials have shown that such adjuvants can stimulate both humoral and cell mediated immune responses.
SEPPIC W/O adjuvants are compatible with inactivated and recombinant antigens.
MONTANIDE™ ISA W/O (non exhaustive listing)
|Mineral oil||MONTANIDE™ ISA 61 VG
MONTANIDE™ ISA 50 V2
|MONTANIDE™ ISA 71 VG
MONTANIDE™ ISA 71 R VG
MONTANIDE™ ISA 70 VG
|MONTANIDE™ ISA 761 VG|
|Non mineral oil||MONTANIDE™ ISA 763 A VG|
Vaccine preparation with MONTANIDE™ ISA for W/O emulsions
Stable W/O vaccine emulsions have to be prepared using a high shear rate.
Compared to Incomplete Freund Adjuvant (IFA), MONTANIDE™ ISA for W/O emulsions render stable emulsions with low viscosity.