Thickening, Stabilizing and Texturizing Agents
Semi-solid forms, intended for topical or oral administration, have several constraints related to their form:
- the stability and homogeneity of the formula over time are more difficult to control than for solid forms and depend greatly on the viscosity of the finished product.
- patient compliance depends in part on the texture of the finished product, especially in the case of topical administration.
The importance of thickening and stabilizing agents
A formulation’s stability is a priority during product development.
In liquid or semi-solid forms, there is a risk of sedimentation of undissolved particles in a suspension, or dephasing in an emulsion. This risk can be greatly reduced if the formula has a high viscosity.
SEPPIC offers a range of thickening and stabilizing agents designed for the pharmaceutical and medical device markets, that can be used to obtain formulations that are stable over time.
The texture of a topical product
A topical product texture is key for its application on the skin.
The nicer the texture, the better the patient’s compliance with regards to the treatment prescribed.
This is why SEPPIC offers innovative systems to help with the formulation of semi-solid forms, particularly texturizing agents which are used to obtain products with a pleasant feel, even with active ingredients that are difficult to formulate.