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Liquid polymeric emulsifier for innovative pharmaceutical "Gel-in-Oil" emulsion and for W/O emulsion

Made of raw materials compliant to the European Pharmacopoeia (Ph. Eur.)

Simaline L80 is a high molecular weight emulsifier imparting robustness and a pleasant sensory profile to innovative Gel-in-oil emulsions and traditional W/O emulsions. 

Its liquid nature makes for easy handling for sampling, manufacturing and cleaning operations.

Chemical name: Sorbitan Oleate & PEG-30 dipolyhydroxystearate 

Dose: 1.5% to 4%

Applications: Topical, transdermal, vaginal, rectal


Vehicle for high quantities of polar solvents

The polymeric nature of Simaline L80 is essential to formulate a Geltrap™, emulsifying a high content of aqueous internal phase (> 80%) into a Gel-in-Oil emulsion.

This dosage form can incorporate
high quantities of polar solvents to promote the solubilization and skin penetration of APIs:

  • > 50% PEG-400
  • > 40% Transcutol® P (Diethylene glycol monoethyl ether)
  • > 80% Propylene glycol
  • > 60% Glycerin

Geltrap™ can also be a solution for topical formulation of water-sensitive APIs into an anhydrous vehicle.

Promoting patient compliance

The Geltrap™ is a solution to improve the sensory profile of your emulsions even in presence of high quantities of solvents, thanks to its unique texture:

  • Fresh touch
  • Non-greasy, non-sticky
  • Easy skin spreading
  • Good emolliency even with only 10% of oil phase

Value-adding benefits for topical drugs and medical devices

  • API solubilization & skin delivery thanks to its compatibility with solvents & penetration enhancers
  • Moisturizing & emollient vehicle for skin disorders linked to disease (e.g. atopic dermatitis, psoriasis, ichthyosis, ...) or treatment (i.e. retinoids, corticoids, ...)
  • Ideal sensory profile for pain relief with moderate to long playtime and fresh touch for quick relief
  • Mucosal applications: water-resistance property for longer contact time

Cost, energy and time-saving technology

The Geltrap™ can be a cost-friendly alternative and a true ally at laboratory and industrial scale:

  • The possibility of a dosage form rich in water, up to 95% content
  • Room-temperature, low shear and quick emulsification process thanks to Simaline L80 polymeric nature
  • Simaline L80: a liquid emulsifier for an easier handling / manufacturing / cleaning


Safety data sheet

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