
SEPITRAP™
Powder solubilizing agent for solid oral forms
Powder solubilizing agent for solid oral forms
SEPITRAP™ offers new prospects for formulation and improving the bioavailability of active ingredients with low solubility.
SEPITRAP™ is a micro-encapsulated solubilizer in powder form designed to simplify the manufacturing of solid oral form drugs. It is manufactured by adsorption of the solubilizer in liquid form on a porous support.
SEPITRAP™ is both a solid solubilizer and a compression agent. It is a functional excipient designed specifically to simplify manufacturing of dry-form drugs while improving bioavailability of the active ingredient.
There are two solubilizers in the SEPITRAP™ range:
Grade | Surfactant | Porous Mineral Carrier |
---|---|---|
SEPITRAP™ 80 | Polysorbate 80 (45-65%) |
Magnesium Aluminometasilicate (35-55%) |
SEPITRAP™ 4000 | Polyoxyl 40 hydrogenated castor oil (55-75%) | Magnesium Aluminometasilicate (25-45%) |
All the components of SEPITRAP™ comply with USP-NF. SEPITRAP™ is manufactured in accordance with IPEC GMP standards and is certified EXCiPACT.
The regulatory and quality package is available on request.
Designed for solid forms such as tablets and capsules, SEPITRAP™ can be used in direct compression procedures without impacting the hardness and disintegration of the formed tablets.
There are two kinds of benefits: bioavailability enhancement and manufacturing process optimization:
SEPITRAP is manufactured using a patented technology
SEPITRAP™ can be used to formulate tablets by direct compression but can also be used in the formulation of hard capsules.
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