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SEPINEO™ P 600 is a thickening, emulsifying and stabilizing polymer
Acrylamide/Sodium Acryloyldimethyl Taurate Copolymer/Isohexadecane & Polysorbate 80

SEPINEO™ P 600 is a 3-in-1 polymer: thickening, emulsifying and stabilizing. Ready-to-use, it is designed for the formulation of gels and creams and is very easy to implement.

SEPINEO™ P 600, an essential polymer

SEPINEO™ P 600 is an essential thickening agent for pharmaceutical formulations. It is easy to use as it does not require neutralization or rehydration steps when developing new gels, creams, simple or multiple emulsions for:

  • Formulas for topical application with drug or medical device status
  • Formulas with high solvent content, anhydrous or with rich oily phases
  • Products composed of heat- or water-sensitive ingredients

A 3-in-1 polymer

An excellent thickener

  • Stable over a wide pH range (3-11)
  • Compatible with a large number of solvents: ethanol, propylene glycol, glycerine
  • Compatible with a large number of active ingredients
  • Synergistic effects with other pharmaceutical thickeners

Stabilizer - Emulsifier

  • No prior HLB calculation required
  • Suitable for polar and nonpolar oils, essential oils and esters
  • Can be used to formulate innovative cream-gels (up to 35-40% fatty phase)
  • Co-stabilizing role: improves the stability of all types of O/W emulsions from as little as 0.5%

Texturizing agent

  • Improves the sensory profile and appearance of a formula from as little as 0.2%
  • Rheofluidifying behaviour providing a finished product which is easy to spread

Easy to use

SEPINEO™ P 600 is presented in liquid form. It is pre-neutralized and no HLB calculation is required.

SEPINEO™ P 600 is easy to work with: aqueous dilution at room temperature, no high shear needed.

Being nonthixotropic, it allows flexibility in the process and equipment used.

The recommended quantity in a formula ranges from 0.2% to 5%.

How to use SEPINEO™ P 600?

sepineo p600


Safety Data Sheet


SEPINEO™ P 600 is designed solely for topical pharmaceutical applications (skin and anal and vaginal mucosa).

It can be used in pharmaceutical or medical device status products.

SEPINEO™ P 600 has a Type IV DMF and is registered in the Inactive Ingredient Database.

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SEPINEO™ D.E.R.M: thickening, stabilizing and texturizing agent
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