SEPISMART™ SR

Excipient from natural origin for sustained release tablets/hard capsules formulation

SEPISMART™ SR is a ready-to-use excipient for sustained release tablet and capsule formulations.
It is a synergistic combination of natural co-processed gums, specially designed for Nutrition applications.

A valuable solution for food supplements

The sustained release technology allows the delivery of an effective amount of active ingredient over time and at a continuous rate.

Sustained release formulations offer a wide range of benefits including:

Optimizing the dosage of active ingredients in the formulation
Enhancing the absorption of nutrients with low bioavailability
Providing high value solutions and marketing differentiation to formulators
Avoiding any peak of active ingredients concentration with potential adverse effects
Reducing number of intakes for the consumers and improving consumer compliance

Excellent sustained release properties

The carefully selected combination of natural gums allows SEPISMART™ SR to swell immediately in the presence of water and form a thick gel layer around the tablet.
As a result, the soluble active ingredients diffuse slowly through the gel layer whereas the insoluble ones are released gradually by tablet erosion.

Easy-to-use in direct compression

Thanks to the synergistic effect of the gums and the process used, SEPISMART™ SR is easy-to-use in direct compression.
SEPISMART™ SR has an excellent flowability and can be easily processed.
Tablets containing SEPISMART™ SR show excellent results in terms of hardness and friability at low compression forces.

Tablets formulated with SEPISMART™ SR in direct compression can then be coated if needed without altering the sustained release properties. It is fully compatible with:

functional coating agents such as SEPIFILM™ LP when the active ingredient requires moisture protection
aesthetic coating agents such as SEPIFILM NAT™ COL giving bright, stable and natural colors to the tablets