Seppic launches Simaline L80, its new liquid emulsifier for topical drugs and medical devices

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  • July 5, 2021
  • 2 mins of read time

Seppic launches Simaline L80, its new liquid emulsifier for topical drugs and medical devices

The main challenge that formulation scientists are facing in topical drug development is to build a dosage form that can stabilize and deliver APIs without compromising on patient compliance.

Made from raw materials compliant to the European Pharmacopoeia, Simaline L80 in combination with Sepineo™ polymer range is a new solution to formulate a dosage form associating superior solvent/penetration enhancer compatibility, a unique texture and ease of manufacturing.  With Simaline L80 and Sepineo™ Polymers, the  Geltrap™ ”Gel-in-oil”  patented concept associates excipients with Pharmacopoeia-compliance or with precedence of use in drugs to offer new technical solutions.

Solvents and penetration enhancers are essential for a successful solubilization and skin delivery of APIs, though they have a significant impact on the stability of the formula. Geltrap™ emulsion is a solution to formulate major pharmaceutical solvents and penetration enhancers even at high concentrations (PEG-400, diethylene glycol monoethyl ether, propylene glycol, glycerin, …).

The performance of “Gel-in-Oil” emulsions comes along with a unique texture, to guarantee an optimal patient compliance: a fresh, non-greasy touch even with high content of solvents, easy skin spreading, moisturizing and emollient, …

The polymeric character of Simaline L80 is the key to the stability of Geltrap™ emulsions, from the most difficult conditions (room-temperature, low shear manufacturing) to traditional emulsion formulation conditions. The liquid form of Simaline L80 makes for easy handling at all stages of the product development and manufacturing.