
METOLOSE® SR / TYLOPUR® SR
High-viscosity hypromellose for forming hydrophilic matrixes
High-viscosity hypromellose for forming hydrophilic matrixes
The METOLOSE® SR/ TYLOPUR® SR range is used in the manufacture of hydrophilic matrixes for the sustained release of active ingredients. The METOLOSE® SR/ TYLOPUR® SR range from SHIN ETSU is compliant with Ph.Eur, JP and USP.
The hydrophilic matrix system is the simplest and cheapest controlled release technology for oral forms.
Comprised of a high-viscosity, water-soluble polymer (HPMC), the products in the METOLOSE® SR/ TYLOPUR® SR range are used in hydrophilic matrixes to control the release of active substances in the body.
The products in the METOLOSE® SR/ TYLOPUR® SR range have many properties:
The products in the METOLOSE® SR/ TYLOPUR® SR range can be used in direct compression or wet granulation.
The type of substitution for METOLOSE® SR/ TYLOPUR® SR impacts the product's hydration and the strength of the gel formed.
The greater the viscosity, the stronger the gel and the slower the dissolution.
Type | Viscosity (cP) | Methoxy (%) | Hydroxypropoxy (%) |
---|---|---|---|
METOLOSE SR & TYLOPUR SR
|
100 4000 15000 100000 |
23 | 10 |
The products in the METOLOSE® SR/ TYLOPUR® SR range are manufactured in accordance with the Good Manufacturing Practices applicable to excipients.
All the regulatory and quality documents required for registration are available on request.
The Japanese company SHIN ETSU is a leader in cellulose chemistry.
SHIN ETSU develops pharmaceutical excipients and particularly cellulosic polymers for a range of applications such as film-coating, compression and matrices. METOLOSE® SR range is produced in Japan while TYLOPUR® SR range is produced in Germany. Both sites can be used as back-up site, securing your supply chain activities.
SEPPIC™ distributes SHIN ETSU products in Western and Southern Europe and several other countries.
Would you like a sample of this ingredient ?
Request