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EU07470P Anhydrous Cream-gel

EU07470P Anhydrous Cream-gel

Anhydrous dosage form with easy skin spreading and improved sensorial profile, for the formulation of water-sensitive APIs

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Often used as a way to prevent degradation of water-sensitive APIs, anhydrous formulation also comes with several constraints. The high quantities of solvents, mostly glycol-based, and lipophilic excipients involved can be a challenge to stabilize and give texture adverse to a good patient compliance.


Stabilization of more than 80% of solvents

As an inverse latex polymer SEPINEO™ D.E.R.M has strong thickening capacities of polar solvents, including PEG 400, diethylene glycol monoethyl ether, propylene glycol, glycerin, ethanol, …

Oil-stabilization, unique amongst pharmaceutical polymers

Through its elastic polymer network SEPINEO™ D.E.R.M can stabilize up to 30% of any kind of oil phase without additional surfactant addition, in a simple and flexible process.

Texture improvement of anhydrous formulas

Addition of SEPINEO™ D.E.R.M leads to an optimization of the texture of your anhydrous formulas, for better patient compliance.

  • Easy skin spreading thanks to its rheofluidifying profile
  • Less-greasy, less-sticky touch