
EU07679P Anhydrous Gel-In-Oil Geltrap™ Emulsion
Innovative dosage form for anhydrous formulas with better texture
Innovative dosage form for anhydrous formulas with better texture
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Often used as a way to prevent degradation of water-sensitive APIs, anhydrous formulation also comes with several constraints. The high quantities of solvents, mostly glycol-based, and lipophilic excipients involved can be a challenge to stabilize and give texture adverse to a good patient compliance.
Through the combination of inverse emulsion polymer SEPINEO™ P 600 and polymeric emulsifier SIMALINE L80, a Gel-in-oil dosage form is majorly composed of an hydrophilic internal phase (> 80%) which can contain high amounts of polar solvents including glycerin, PEG 400, diethylene glycol monoethyl ether, propylene glycol, …
A Gel-in-oil dosage form drastically improves the touch of formulations, even with a high load of solvents inside.
A Gel-in oil emulsion comes with patient benefits specific to this dosage form: