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Vascular protection

CORDIART™ is a natural rutinoside extract from citrus fruit, supporting healthy circulation. A clinical study has shown the beneficial effect of CORDIART™ on endothelial function, inflammatory status and metabolic parameters.

Unique mechanism of action

CORDIART™ activates the production of Nitric Oxide (NO) by the endothelium, which in turn sends a signal to the vascular smooth muscles to relax. This induces vasodilatation of the blood vessels and supports a healthy circulation. More precisely, CORDIART™ stimulates eNOS activity and therefore helps to restore the physiological NO production.

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Clinically studied action

CORDIART™ has shown in a randomized placebo controlled trial to significantly improve Flow Mediated Dilation (FMD), which is a direct marker of endothelial function. Three weeks of intervention resulted in a better response of the arteries to changes in blood flow. Subjects who received CORDIART™ showed a 20% higher FMD-score compared to subjects who received a placebo.


BIOACTOR develops clinically tested health ingredients for use in dietary supplements and functional food.

SEPPIC distributes BIOACTOR products in North America and Italy.


Safety Data Sheet

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